Gene Ontology

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 6261
• Symbol: RYR1
• Description: ryanodine receptor 1

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
6261	GO:0001666	IDA	involved_in	response to hypoxia	19120137	Process
6261	GO:0051209	IMP	involved_in	release of sequestered calcium ion into cytosol	11741831,16163667	Process
6261	GO:0071313	IMP	involved_in	cellular response to caffeine	16163667,26115329	Process

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
6261	GO:0005219	IDA	enables	ryanodine-sensitive calcium-release channel activity	22480578	Function
6261	GO:0005219	IMP	enables	ryanodine-sensitive calcium-release channel activity	11741831,16163667,26115329	Function
6261	GO:0048763	IMP	enables	calcium-induced calcium release activity	26115329	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
6261	GO:0005737	IDA	located_in	cytoplasm	11206130	Component
6261	GO:0005886	IDA	located_in	plasma membrane	11206130	Component
6261	GO:0005938	IDA	located_in	cell cortex	11206130	Component
6261	GO:0031674	IDA	located_in	I band	11206130	Component
6261	GO:0033017	IDA	located_in	sarcoplasmic reticulum membrane	7556644	Component
6261	GO:0070062	HDA	located_in	extracellular exosome	19056867	Component