Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 64116
  • Symbol: SLC39A8
  • Description: solute carrier family 39 member 8

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
64116 GO:0005765 IDA located_in lysosomal membrane 18390834,19401385 Component
64116 GO:0005886 IDA located_in plasma membrane 18390834 Component
64116 GO:0016323 IDA located_in basolateral plasma membrane 31699897 Component
64116 GO:0016324 IDA located_in apical plasma membrane 31699897 Component
64116 GO:0031090 IDA located_in organelle membrane 12504855 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
64116 GO:0006355 IMP acts_upstream_of regulation of DNA-templated transcription 29337306 Process
64116 GO:0006829 IMP involved_in zinc ion transport 12504855 Process
64116 GO:0006882 IDA involved_in intracellular zinc ion homeostasis 19401385 Process
64116 GO:0030198 IMP acts_upstream_of extracellular matrix organization 29337306 Process
64116 GO:0042391 IMP involved_in regulation of membrane potential 18390834 Process
64116 GO:0043124 IMP acts_upstream_of_negative_effect negative regulation of I-kappaB kinase/NF-kappaB signaling 23403290 Process
64116 GO:0050728 IMP acts_upstream_of_negative_effect negative regulation of inflammatory response 23403290 Process
64116 GO:0070574 IDA involved_in cadmium ion transmembrane transport 27466201 Process
64116 GO:0071421 IMP involved_in manganese ion transmembrane transport 28481222,29453449,31699897 Process
64116 GO:0071577 IDA involved_in zinc ion transmembrane transport 19401385 Process
64116 GO:0071577 IMP involved_in zinc ion transmembrane transport 18390834 Process
64116 GO:0071578 IMP involved_in zinc ion import across plasma membrane 23403290,29337306 Process
64116 GO:0097080 IDA involved_in plasma membrane selenite transport 27166256 Process
64116 GO:0098711 IDA involved_in iron ion import across plasma membrane 22898811 Process
64116 GO:0098849 IMP involved_in cellular detoxification of cadmium ion 27466201 Process
64116 GO:1990540 IMP involved_in mitochondrial manganese ion transmembrane transport 29453449 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
64116 GO:0140410 IDA enables monoatomic cation:bicarbonate symporter activity 22898811,27166256,27466201,28481222,29453449,31699897..... Function