Gene Ontology

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 6426
• Symbol: SRSF1
• Description: serine and arginine rich splicing factor 1

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
6426	GO:0000380	IDA	involved_in	alternative mRNA splicing, via spliceosome	8940107	Process
6426	GO:0000395	IDA	involved_in	mRNA 5'-splice site recognition	8940107,9885563	Process

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
6426	GO:0003723	HDA	enables	RNA binding	22658674,22681889	Function
6426	GO:0003723	IDA	enables	RNA binding	19561594	Function
6426	GO:0003723	IPI	enables	RNA binding	20797886	Function
6426	GO:0003729	IDA	enables	mRNA binding	21984414	Function
6426	GO:0005515	IPI	enables	protein binding	9237760,9885563,10196197,15184380,15243141,15652350,15798186,1.....	Function
6426	GO:0044547	IPI	enables	DNA topoisomerase binding	9611241	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
6426	GO:0005634	HDA	located_in	nucleus	21630459	Component
6426	GO:0005634	IDA	located_in	nucleus	21984414,24449914	Component
6426	GO:0005654	IDA	located_in	nucleoplasm	9885563	Component
6426	GO:0005737	IDA	located_in	cytoplasm	24449914	Component
6426	GO:0016607	IDA	located_in	nuclear speck	20797886,24644279	Component
6426	GO:0071013	IDA	part_of	catalytic step 2 spliceosome	11991638	Component