Gene Ontology

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 65114
  • Symbol: Vps35
  • Description: VPS35 retromer complex component

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
65114 GO:0005515 IPI enables protein binding 15965486,18160348,18480253,20923837,21040701,23055941,23395371..... Function
65114 GO:0031748 IPI enables D1 dopamine receptor binding 27460146 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
65114 GO:0005737 IDA located_in cytoplasm 17239604 Component
65114 GO:0005737 IMP located_in cytoplasm 26203154 Component
65114 GO:0005768 IDA located_in endosome 26965651 Component
65114 GO:0014069 IDA located_in postsynaptic density 17114649 Component
65114 GO:0030904 IDA part_of retromer complex 21040701 Component
65114 GO:0043005 IMP located_in neuron projection 26203154 Component
65114 GO:0043025 IMP located_in neuronal cell body 26203154 Component
65114 GO:0045202 IDA located_in synapse 29118110 Component
65114 GO:0048471 IMP located_in perinuclear region of cytoplasm 26203154 Component
65114 GO:0098691 IDA is_active_in dopaminergic synapse 30155515 Component
65114 GO:0098691 IEP is_active_in dopaminergic synapse 30155515 Component
65114 GO:0098691 IMP is_active_in dopaminergic synapse 30155515 Component
65114 GO:0098793 IDA is_active_in presynapse 29445238 Component
65114 GO:0098794 IDA is_active_in postsynapse 26521016,29445238 Component
65114 GO:0098794 IEP is_active_in postsynapse 26521016 Component
65114 GO:0098794 IMP is_active_in postsynapse 26521016 Component
65114 GO:0098794 IPI is_active_in postsynapse 26521016 Component
65114 GO:0098978 IDA is_active_in glutamatergic synapse 26521016,28384478 Component
65114 GO:0098978 IEP is_active_in glutamatergic synapse 26521016 Component
65114 GO:0098978 IMP is_active_in glutamatergic synapse 26521016,28384478 Component
65114 GO:0098978 IPI is_active_in glutamatergic synapse 26521016 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
65114 GO:0007040 IMP involved_in lysosome organization 26203154 Process
65114 GO:0010628 IMP involved_in positive regulation of gene expression 26203154 Process
65114 GO:0010629 IMP involved_in negative regulation of gene expression 26203154 Process
65114 GO:0031648 IMP involved_in protein destabilization 26203154 Process
65114 GO:0032463 IMP involved_in negative regulation of protein homooligomerization 26203154 Process
65114 GO:0033365 IMP involved_in protein localization to organelle 26203154 Process
65114 GO:0050804 IDA involved_in modulation of chemical synaptic transmission 30155515 Process
65114 GO:0050804 IEP involved_in modulation of chemical synaptic transmission 30155515 Process
65114 GO:0050804 IMP involved_in modulation of chemical synaptic transmission 30155515 Process
65114 GO:0050882 IMP involved_in voluntary musculoskeletal movement 26203154 Process
65114 GO:0061357 IMP involved_in positive regulation of Wnt protein secretion 18160348 Process
65114 GO:0090128 IDA involved_in regulation of synapse maturation 26521016 Process
65114 GO:0090128 IMP involved_in regulation of synapse maturation 26521016 Process
65114 GO:0090263 IGI involved_in positive regulation of canonical Wnt signaling pathway 17239604 Process
65114 GO:0090326 IMP involved_in positive regulation of locomotion involved in locomotory behavior 26203154 Process
65114 GO:0098887 IDA involved_in neurotransmitter receptor transport, endosome to postsynaptic membrane 28384478 Process
65114 GO:0098887 IMP involved_in neurotransmitter receptor transport, endosome to postsynaptic membrane 28384478 Process
65114 GO:0099003 IDA involved_in vesicle-mediated transport in synapse 28384478 Process
65114 GO:0099003 IMP involved_in vesicle-mediated transport in synapse 28384478 Process
65114 GO:0099639 IMP involved_in neurotransmitter receptor transport, endosome to plasma membrane 27460146 Process
65114 GO:0150052 IDA involved_in regulation of postsynapse assembly 26521016 Process
65114 GO:0150052 IMP involved_in regulation of postsynapse assembly 26521016 Process
65114 GO:1901215 IMP involved_in negative regulation of neuron death 26203154 Process
65114 GO:1903181 IMP involved_in positive regulation of dopamine biosynthetic process 26203154 Process
65114 GO:1903828 IMP involved_in negative regulation of protein localization 26203154 Process
65114 GO:1905166 IMP involved_in negative regulation of lysosomal protein catabolic process 26203154 Process