Gene Ontology

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 6558
• Symbol: SLC12A2
• Description: solute carrier family 12 member 2

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
6558	GO:0005515	IPI	enables	protein binding	17721439,22570591,24555568,35044719	Function
6558	GO:0008511	IDA	enables	sodium:potassium:chloride symporter activity	33597714	Function
6558	GO:0008519	IDA	enables	ammonium transmembrane transporter activity	12946942,18032481	Function
6558	GO:0015377	IDA	enables	chloride:monoatomic cation symporter activity	7629105	Function
6558	GO:0019901	IPI	enables	protein kinase binding	12740379,16669787	Function
6558	GO:0046873	IDA	enables	metal ion transmembrane transporter activity	7629105,15347682	Function
6558	GO:0051087	IPI	enables	protein-folding chaperone binding	15347682	Function
6558	GO:0051879	IPI	enables	Hsp90 protein binding	15347682	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
6558	GO:0005886	IDA	is_active_in	plasma membrane	7629105	Component
6558	GO:0009925	IDA	located_in	basal plasma membrane	17478539	Component
6558	GO:0016324	IDA	located_in	apical plasma membrane	17478539	Component
6558	GO:0016328	IDA	located_in	lateral plasma membrane	17478539	Component
6558	GO:0030659	IDA	located_in	cytoplasmic vesicle membrane	17478539	Component
6558	GO:0043005	IDA	located_in	neuron projection	16227993	Component
6558	GO:0043025	IDA	located_in	neuronal cell body	16227993	Component
6558	GO:0070062	HDA	located_in	extracellular exosome	19199708,20458337	Component
6558	GO:0071944	IDA	located_in	cell periphery	16227993	Component
6558	GO:1903561	HDA	located_in	extracellular vesicle	24769233	Component

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
6558	GO:0010818	IMP	involved_in	T cell chemotaxis	27400149	Process
6558	GO:0030321	IDA	involved_in	transepithelial chloride transport	12946942	Process
6558	GO:0070634	IDA	involved_in	transepithelial ammonium transport	18032481	Process
6558	GO:0072488	IDA	involved_in	ammonium transmembrane transport	12946942,18032481	Process
6558	GO:0098659	IDA	involved_in	inorganic cation import across plasma membrane	7629105,15347682	Process
6558	GO:1990869	IMP	involved_in	cellular response to chemokine	27400149	Process