Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 659
  • Symbol: BMPR2
  • Description: bone morphogenetic protein receptor type 2

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
659 GO:0001649 IMP involved_in osteoblast differentiation 22684006 Process
659 GO:0001935 IMP involved_in endothelial cell proliferation 25187962 Process
659 GO:0001938 IMP involved_in positive regulation of endothelial cell proliferation 17992660 Process
659 GO:0002063 IMP involved_in chondrocyte development 9442116 Process
659 GO:0003085 IMP involved_in negative regulation of systemic arterial blood pressure 18364108 Process
659 GO:0007178 IDA involved_in transmembrane receptor protein serine/threonine kinase signaling pathway 12045205 Process
659 GO:0009267 IEP involved_in cellular response to starvation 15657086 Process
659 GO:0010595 IMP involved_in positive regulation of endothelial cell migration 17992660 Process
659 GO:0010628 IMP acts_upstream_of positive regulation of gene expression 22684006 Process
659 GO:0010634 IDA involved_in positive regulation of epithelial cell migration 12819188 Process
659 GO:0010862 IMP involved_in positive regulation of pathway-restricted SMAD protein phosphorylation 17992660,19366699 Process
659 GO:0014916 IMP involved_in regulation of lung blood pressure 18364108 Process
659 GO:0030308 IDA involved_in negative regulation of cell growth 12819188 Process
659 GO:0030501 IMP involved_in positive regulation of bone mineralization 18436533 Process
659 GO:0030509 IDA involved_in BMP signaling pathway 18436533 Process
659 GO:0030509 IGI involved_in BMP signaling pathway 18382765 Process
659 GO:0030509 IMP involved_in BMP signaling pathway 9442116,12045205,19366699 Process
659 GO:0030513 IMP involved_in positive regulation of BMP signaling pathway 17992660 Process
659 GO:0042127 IMP involved_in regulation of cell population proliferation 11502704 Process
659 GO:0045669 IMP involved_in positive regulation of osteoblast differentiation 18436533 Process
659 GO:0045944 IMP involved_in positive regulation of transcription by RNA polymerase II 12045205,18326817 Process
659 GO:0048662 IMP involved_in negative regulation of smooth muscle cell proliferation 18382765 Process
659 GO:0060391 IGI acts_upstream_of_or_within positive regulation of SMAD protein signal transduction 18382765 Process
659 GO:0071773 IMP involved_in cellular response to BMP stimulus 18326817 Process
659 GO:0072577 IMP involved_in endothelial cell apoptotic process 25187962 Process
659 GO:1902731 IMP involved_in negative regulation of chondrocyte proliferation 9442116 Process
659 GO:2000279 IMP involved_in negative regulation of DNA biosynthetic process 19366699 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
659 GO:0005515 IPI enables protein binding 12045205,15188402,15657086,19229295,19424179,21976273,24407287..... Function
659 GO:0036122 IPI enables BMP binding 21976273 Function
659 GO:0045296 IPI enables cadherin binding 26598555 Function
659 GO:1990782 IPI enables protein tyrosine kinase binding 26598555 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
659 GO:0005615 HDA located_in extracellular space 22664934 Component
659 GO:0005654 IDA located_in nucleoplasm Component
659 GO:0005886 IDA located_in plasma membrane 12045205,15657086,25187962 Component
659 GO:0005901 IMP colocalizes_with caveola 15657086 Component
659 GO:0005912 IDA located_in adherens junction 25468996 Component