Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 6609
  • Symbol: SMPD1
  • Description: sphingomyelin phosphodiesterase 1

Process

Export (tab separated) Export to Excel
GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
6609 GO:0001778 IDA involved_in plasma membrane repair 20530211 Process
6609 GO:0006685 IDA involved_in sphingomyelin catabolic process 18815062,20807762,22573858 Process
6609 GO:0009615 IDA involved_in response to virus 22573858 Process
6609 GO:0010212 IMP involved_in response to ionizing radiation 8706124 Process
6609 GO:0023021 IMP involved_in termination of signal transduction 19279008 Process
6609 GO:0034340 IDA involved_in response to type I interferon 20807762 Process
6609 GO:0034612 IDA involved_in response to tumor necrosis factor 20807762 Process
6609 GO:0034644 IDA involved_in cellular response to UV 17303575 Process
6609 GO:0035307 IMP involved_in positive regulation of protein dephosphorylation 19279008 Process
6609 GO:0042060 IDA involved_in wound healing 20530211 Process
6609 GO:0043065 IMP involved_in positive regulation of apoptotic process 8706124 Process
6609 GO:0043407 IMP involved_in negative regulation of MAP kinase activity 19279008 Process
6609 GO:0045807 IDA involved_in positive regulation of endocytosis 20530211 Process
6609 GO:0046513 IDA involved_in ceramide biosynthetic process 17303575,18815062,20807762,33163980 Process
6609 GO:0046513 IMP involved_in ceramide biosynthetic process 8706124,19279011 Process
6609 GO:0046598 IDA involved_in positive regulation of viral entry into host cell 33163980 Process
6609 GO:0046718 IDA acts_upstream_of viral entry into host cell 33163980 Process
6609 GO:0046718 IDA acts_upstream_of_positive_effect viral entry into host cell 33163980 Process
6609 GO:0046718 IDA involved_in viral entry into host cell 22573858 Process
6609 GO:0070555 IDA involved_in response to interleukin-1 20807762 Process
6609 GO:0071277 IDA involved_in cellular response to calcium ion 20530211 Process

Function

Export (tab separated) Export to Excel
GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
6609 GO:0004767 IDA enables sphingomyelin phosphodiesterase activity 9660788,21098024,22573858,33163980 Function
6609 GO:0005515 IPI enables protein binding 16787399,21157428 Function
6609 GO:0008270 IDA enables zinc ion binding 8702487,9660788 Function
6609 GO:0061750 IDA enables acid sphingomyelin phosphodiesterase activity 8702487,17303575,18815062,20807762 Function

Component

Export (tab separated) Export to Excel
GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
6609 GO:0005615 IDA is_active_in extracellular space 33163980 Component
6609 GO:0005615 IDA located_in extracellular space 8702487,9660788,16787399,17303575,20530211,20807762,21098024,2..... Component
6609 GO:0005764 IDA is_active_in lysosome 33163980 Component
6609 GO:0005764 IDA located_in lysosome 9660788,16787399,18815062,20530211,20807762,20956541,21098024,..... Component
6609 GO:0005768 IDA located_in endosome 20956541 Component
6609 GO:0005886 IDA located_in plasma membrane 20956541 Component
6609 GO:0036019 IDA located_in endolysosome 17303575 Component
6609 GO:0070062 HDA located_in extracellular exosome 23533145 Component