Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 6647
  • Symbol: SOD1
  • Description: superoxide dismutase 1

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
6647 GO:0000303 IDA involved_in response to superoxide 16790527 Process
6647 GO:0001819 IDA involved_in positive regulation of cytokine production 15544046 Process
6647 GO:0006801 IDA involved_in superoxide metabolic process 12551919 Process
6647 GO:0010033 IDA involved_in response to organic substance 12921788 Process
6647 GO:0032930 IDA involved_in positive regulation of superoxide anion generation 18219391 Process
6647 GO:0043085 IDA involved_in positive regulation of catalytic activity 17324120 Process
6647 GO:0043087 IDA involved_in regulation of GTPase activity 18219391 Process
6647 GO:0045541 IDA involved_in negative regulation of cholesterol biosynthetic process 15473258 Process
6647 GO:0045859 IDA involved_in regulation of protein kinase activity 16254550 Process
6647 GO:0050665 IDA involved_in hydrogen peroxide biosynthetic process 15544046 Process
6647 GO:0051881 IMP involved_in regulation of mitochondrial membrane potential 16790527 Process
6647 GO:0060047 IDA involved_in heart contraction 9539776 Process
6647 GO:0072593 IDA involved_in reactive oxygen species metabolic process 24140062 Process
6647 GO:1902177 IMP involved_in positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway 12551919 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
6647 GO:0004784 IDA enables superoxide dismutase activity 12551919,15544046,17324120,24140062,24567322 Function
6647 GO:0005507 IDA enables copper ion binding 17008312 Function
6647 GO:0005515 IPI enables protein binding 12968035,16369483,16595634,16790527,19171884,20195357,21252941..... Function
6647 GO:0008270 IDA enables zinc ion binding 17381088 Function
6647 GO:0030346 IDA enables protein phosphatase 2B binding 17324120 Function
6647 GO:0031267 IDA enables small GTPase binding 18219391 Function
6647 GO:0042802 IPI enables identical protein binding 17592131,19022905,19171884,19369197,19828437,21257910,23831581..... Function
6647 GO:0043167 EXP enables ion binding 19800308 Function
6647 GO:0051087 IPI enables protein-folding chaperone binding 9726962 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
6647 GO:0005615 IDA located_in extracellular space 9453566 Component
6647 GO:0005634 HDA located_in nucleus 21630459 Component
6647 GO:0005634 IDA located_in nucleus 1332049,9726962,17504823,22496122,24023695 Component
6647 GO:0005654 IDA located_in nucleoplasm Component
6647 GO:0005737 IDA located_in cytoplasm 1332049,9726962,11527942,17077646,17504823,18809582,19741096,2..... Component
6647 GO:0005739 IDA located_in mitochondrion 16790527,19741096 Component
6647 GO:0005777 IDA located_in peroxisome 1332049 Component
6647 GO:0005829 IDA located_in cytosol 16790527 Component
6647 GO:0005886 IDA colocalizes_with plasma membrane 17077646,17324120 Component
6647 GO:0031410 IDA located_in cytoplasmic vesicle 17077646 Component
6647 GO:0032839 IDA located_in dendrite cytoplasm 17324120 Component
6647 GO:0032991 IDA part_of protein-containing complex 17324120 Component
6647 GO:0043025 IDA located_in neuronal cell body 17324120 Component
6647 GO:0070062 HDA located_in extracellular exosome 19056867,23533145 Component