Gene Ontology

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 6678
• Symbol: SPARC
• Description: secreted protein acidic and cysteine rich

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
6678	GO:0001937	IDA	involved_in	negative regulation of endothelial cell proliferation	12867428	Process
6678	GO:0010595	IDA	involved_in	positive regulation of endothelial cell migration	12867428	Process
6678	GO:0016525	IDA	involved_in	negative regulation of angiogenesis	12867428	Process
6678	GO:0022604	IDA	involved_in	regulation of cell morphogenesis	15389586	Process

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
6678	GO:0005509	IDA	enables	calcium ion binding	7034958	Function
6678	GO:0005515	IPI	enables	protein binding	3402455,18808384,19011090,20926826	Function
6678	GO:0005518	IDA	enables	collagen binding	7034958,9501084	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
6678	GO:0005576	HDA	located_in	extracellular region	27068509	Component
6678	GO:0005737	IDA	NOT located_in	cytoplasm	1737102	Component
6678	GO:0005737	IDA	located_in	cytoplasm	3400777,11856645,15389586	Component
6678	GO:0005739	IDA	NOT located_in	mitochondrion	1737102	Component
6678	GO:0005886	IDA	NOT located_in	plasma membrane	1737102	Component
6678	GO:0009986	IDA	located_in	cell surface	3400777,15389586	Component
6678	GO:0016363	IDA	located_in	nuclear matrix	15389586	Component
6678	GO:0031091	IDA	located_in	platelet alpha granule	1737102	Component
6678	GO:0031092	IDA	located_in	platelet alpha granule membrane	1737102	Component
6678	GO:0043231	IDA	located_in	intracellular membrane-bounded organelle		Component
6678	GO:0062023	HDA	located_in	collagen-containing extracellular matrix	28327460	Component