Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 675
  • Symbol: BRCA2
  • Description: BRCA2 DNA repair associated

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
675 GO:0000152 IDA part_of nuclear ubiquitin ligase complex 14636569 Component
675 GO:0000781 IDA located_in chromosome, telomeric region 21076401 Component
675 GO:0000800 IDA located_in lateral element 9774970 Component
675 GO:0005634 IDA located_in nucleus 9560268,9774970,14636569,17286961,26833090 Component
675 GO:0005654 IDA located_in nucleoplasm Component
675 GO:0005813 IDA located_in centrosome 17286961,21276791 Component
675 GO:0005829 IDA located_in cytosol Component
675 GO:0030141 IDA located_in secretory granule 8589722 Component
675 GO:0032991 IDA part_of protein-containing complex 9774970,26833090 Component
675 GO:0033593 IDA part_of BRCA2-MAGE-D1 complex 15930293 Component
675 GO:1990391 IPI part_of DNA repair complex 19369211 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
675 GO:0000724 IDA involved_in double-strand break repair via homologous recombination 20729832,28398198 Process
675 GO:0000724 IMP involved_in double-strand break repair via homologous recombination 21719596 Process
675 GO:0006289 IMP involved_in nucleotide-excision repair 16845393 Process
675 GO:0006302 IMP involved_in double-strand break repair 16845393 Process
675 GO:0033600 IDA involved_in negative regulation of mammary gland epithelial cell proliferation 15930293 Process
675 GO:0045893 IDA involved_in positive regulation of DNA-templated transcription 9126734 Process
675 GO:0051298 IMP involved_in centrosome duplication 17286961 Process
675 GO:0070200 IDA involved_in establishment of protein localization to telomere 21076401 Process
675 GO:0071479 IMP involved_in cellular response to ionizing radiation 14636569 Process
675 GO:1990426 IMP involved_in mitotic recombination-dependent replication fork processing 21076401 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
675 GO:0002020 IPI enables protease binding 15314155 Function
675 GO:0003697 IDA enables single-stranded DNA binding 20729832 Function
675 GO:0004402 IDA NOT enables histone acetyltransferase activity 9824164 Function
675 GO:0005515 IDA enables protein binding 9774970 Function
675 GO:0005515 IPI enables protein binding 9560268,9774970,10373512,10551859,11597317,12242698,12442171,1..... Function
675 GO:0010484 IDA enables histone H3 acetyltransferase activity 9619837 Function
675 GO:0010485 IDA enables histone H4 acetyltransferase activity 9619837 Function
675 GO:0042802 IPI enables identical protein binding 21601571,25282148 Function
675 GO:0043015 IPI enables gamma-tubulin binding 17286961 Function