Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 6794
  • Symbol: STK11
  • Description: serine/threonine kinase 11

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
6794 GO:0000287 IDA enables magnesium ion binding 12805220 Function
6794 GO:0002039 IDA enables p53 binding 11430832 Function
6794 GO:0004674 IDA enables protein serine/threonine kinase activity 11430832,12805220,19892943 Function
6794 GO:0005515 IPI enables protein binding 12595760,12753905,12805220,14676191,17216128,19274086,19513107..... Function
6794 GO:0005524 IDA enables ATP binding 12805220 Function
6794 GO:0030295 IDA enables protein kinase activator activity 19892943 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
6794 GO:0005634 IDA located_in nucleus 12805220,18854309 Component
6794 GO:0005654 IDA located_in nucleoplasm Component
6794 GO:0005737 IDA located_in cytoplasm 11430832,12805220,14517248,17216128,18854309 Component
6794 GO:0005739 IDA located_in mitochondrion 11430832 Component
6794 GO:0005829 IDA located_in cytosol Component
6794 GO:0070062 HDA located_in extracellular exosome 19056867 Component
6794 GO:0140535 IDA part_of intracellular protein-containing complex 12805220 Component
6794 GO:1902554 IPI part_of serine/threonine protein kinase complex 19892943 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
6794 GO:0006468 IDA involved_in protein phosphorylation 12805220,25329316 Process
6794 GO:0006470 IMP involved_in protein dephosphorylation 15731909 Process
6794 GO:0006974 IMP involved_in DNA damage response 25329316 Process
6794 GO:0008285 IMP involved_in negative regulation of cell population proliferation 17216128,25329316 Process
6794 GO:0010508 IMP involved_in positive regulation of autophagy 23878245 Process
6794 GO:0018107 IDA involved_in peptidyl-threonine phosphorylation 12805220 Process
6794 GO:0030010 IMP involved_in establishment of cell polarity 24643070 Process
6794 GO:0030511 IMP involved_in positive regulation of transforming growth factor beta receptor signaling pathway 18311138 Process
6794 GO:0032147 IDA involved_in activation of protein kinase activity 19892943 Process
6794 GO:0032147 IMP involved_in activation of protein kinase activity 15731909 Process
6794 GO:0043276 IMP involved_in anoikis 19622832 Process
6794 GO:0046777 IDA involved_in protein autophosphorylation 11430832 Process
6794 GO:0070314 IDA acts_upstream_of_negative_effect G1 to G0 transition 17216128 Process
6794 GO:0070314 IPI acts_upstream_of_negative_effect G1 to G0 transition 12805220 Process
6794 GO:0071493 IDA involved_in cellular response to UV-B 25329316 Process
6794 GO:0072332 IDA involved_in intrinsic apoptotic signaling pathway by p53 class mediator 11430832 Process
6794 GO:0090090 IMP involved_in negative regulation of canonical Wnt signaling pathway 15731909 Process
6794 GO:1901610 IMP involved_in positive regulation of vesicle transport along microtubule 24643070 Process
6794 GO:1904262 IMP involved_in negative regulation of TORC1 signaling 23878245 Process