Gene Ontology

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 68943
  • Symbol: Pink1
  • Description: PTEN induced putative kinase 1

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
68943 GO:0000287 IDA enables magnesium ion binding 14607334 Function
68943 GO:0004674 IDA enables protein serine/threonine kinase activity 14607334,24652937 Function
68943 GO:0004674 IMP enables protein serine/threonine kinase activity 24784582,25305081 Function
68943 GO:0005515 IPI enables protein binding 31536960 Function
68943 GO:0005524 IDA enables ATP binding 14607334 Function
68943 GO:0016301 IDA enables kinase activity 14607334 Function
68943 GO:0106310 IMP enables protein serine kinase activity 32484300 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
68943 GO:0005739 HDA located_in mitochondrion 18614015 Component
68943 GO:0005739 IDA located_in mitochondrion 31536960 Component
68943 GO:0005743 IDA located_in mitochondrial inner membrane 24652937 Component
68943 GO:0005783 IDA located_in endoplasmic reticulum 31536960 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
68943 GO:0006468 IDA involved_in protein phosphorylation 14607334,32139798 Process
68943 GO:0010310 IMP involved_in regulation of hydrogen peroxide metabolic process 24553947 Process
68943 GO:0010629 IMP involved_in negative regulation of gene expression 24475098 Process
68943 GO:0014046 IMP acts_upstream_of dopamine secretion 17563363 Process
68943 GO:0022904 IMP involved_in respiratory electron transport chain 18687901 Process
68943 GO:0032226 IMP acts_upstream_of_or_within positive regulation of synaptic transmission, dopaminergic 17563363 Process
68943 GO:0033603 IMP acts_upstream_of_or_within positive regulation of dopamine secretion 17563363 Process
68943 GO:0033605 IMP acts_upstream_of_or_within positive regulation of catecholamine secretion 17563363 Process
68943 GO:0034599 IMP involved_in cellular response to oxidative stress 18687901 Process
68943 GO:0035307 IMP involved_in positive regulation of protein dephosphorylation 24553947 Process
68943 GO:0035556 IDA involved_in intracellular signal transduction 14607334 Process
68943 GO:0043523 IMP involved_in regulation of neuron apoptotic process 22511790 Process
68943 GO:0043524 IMP involved_in negative regulation of neuron apoptotic process 18560593,22511790 Process
68943 GO:0045727 IMP involved_in positive regulation of translation 24553947 Process
68943 GO:0050432 IMP acts_upstream_of catecholamine secretion 17563363 Process
68943 GO:0050821 IMP involved_in protein stabilization 19229105 Process
68943 GO:0051091 IMP involved_in positive regulation of DNA-binding transcription factor activity 24553947 Process
68943 GO:0051649 IMP acts_upstream_of establishment of localization in cell 17563363 Process
68943 GO:0071456 IMP involved_in cellular response to hypoxia 24553947 Process
68943 GO:0097237 IMP involved_in cellular response to toxic substance 22511790 Process
68943 GO:1902958 IMP acts_upstream_of_or_within positive regulation of mitochondrial electron transport, NADH to ubiquinone 24652937 Process
68943 GO:1903298 IMP involved_in negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway 24553947 Process