Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 7021
  • Symbol: TFAP2B
  • Description: transcription factor AP-2 beta

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
7021 GO:0000122 IDA involved_in negative regulation of transcription by RNA polymerase II 7559606 Process
7021 GO:0006006 IMP involved_in glucose metabolic process 15940393,16373396,19325541 Process
7021 GO:0008284 IDA involved_in positive regulation of cell population proliferation 17525748 Process
7021 GO:0008285 IDA involved_in negative regulation of cell population proliferation 20607706 Process
7021 GO:0010842 IEP involved_in retina layer formation 20607706 Process
7021 GO:0043066 IDA acts_upstream_of_negative_effect negative regulation of apoptotic process 17525748 Process
7021 GO:0043525 IDA involved_in positive regulation of neuron apoptotic process 20607706 Process
7021 GO:0045444 IEP involved_in fat cell differentiation 16373396 Process
7021 GO:0045595 IDA involved_in regulation of cell differentiation 20607706 Process
7021 GO:0045892 IDA involved_in negative regulation of DNA-templated transcription 20607706 Process
7021 GO:0045893 IDA involved_in positive regulation of DNA-templated transcription 11505339 Process
7021 GO:0045893 IMP involved_in positive regulation of DNA-templated transcription 16373396 Process
7021 GO:0045944 IDA involved_in positive regulation of transcription by RNA polymerase II 7555706,12169688 Process
7021 GO:0050796 IMP involved_in regulation of insulin secretion 15940393,19325541 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
7021 GO:0000978 IDA enables RNA polymerase II cis-regulatory region sequence-specific DNA binding 7555706 Function
7021 GO:0000981 IDA enables DNA-binding transcription factor activity, RNA polymerase II-specific 7555706 Function
7021 GO:0000987 IDA enables cis-regulatory region sequence-specific DNA binding 16373396 Function
7021 GO:0001228 IDA enables DNA-binding transcription activator activity, RNA polymerase II-specific 7559606 Function
7021 GO:0003700 IDA enables DNA-binding transcription factor activity 11505339,12169688,16373396 Function
7021 GO:0005515 IPI enables protein binding 7555706,11694877,12072434,12586840,19115315,32814053..... Function
7021 GO:0042803 IPI enables protein homodimerization activity 11505339 Function
7021 GO:0043565 IDA enables sequence-specific DNA binding 11505339,12169688 Function
7021 GO:0046982 IPI enables protein heterodimerization activity 11505339 Function
7021 GO:1990837 IDA enables sequence-specific double-stranded DNA binding 28473536 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
7021 GO:0005634 IDA located_in nucleus 20607706 Component