Gene Ontology

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 7074
• Symbol: TIAM1
• Description: TIAM Rac1 associated GEF 1

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
7074	GO:0005085	EXP	enables	guanyl-nucleotide exchange factor activity	15721239	Function
7074	GO:0005085	IDA	enables	guanyl-nucleotide exchange factor activity	23109420	Function
7074	GO:0005085	IMP	enables	guanyl-nucleotide exchange factor activity	20361982,25684205	Function
7074	GO:0005515	IPI	enables	protein binding	17440041,21763699,23109420,23395182,32707033	Function
7074	GO:0019900	IPI	enables	kinase binding	23109420	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
7074	GO:0005829	IDA	located_in	cytosol	23109420	Component
7074	GO:0005886	IDA	located_in	plasma membrane	23109420	Component
7074	GO:0005911	IDA	located_in	cell-cell junction	20332120	Component
7074	GO:0044291	IDA	located_in	cell-cell contact zone	20361982	Component

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
7074	GO:0007160	IMP	involved_in	cell-matrix adhesion	20361982	Process
7074	GO:0008284	IDA	involved_in	positive regulation of cell population proliferation	25032858	Process
7074	GO:0010717	IDA	involved_in	regulation of epithelial to mesenchymal transition	20826792	Process
7074	GO:0016477	IMP	involved_in	cell migration	20361982	Process
7074	GO:0016601	IMP	involved_in	Rac protein signal transduction	20361982	Process
7074	GO:0030335	IDA	involved_in	positive regulation of cell migration	25032858	Process
7074	GO:0032092	IDA	involved_in	positive regulation of protein binding	23109420	Process
7074	GO:0065003	IDA	involved_in	protein-containing complex assembly	23109420	Process
7074	GO:0090630	IDA	involved_in	activation of GTPase activity	23109420	Process