Gene Ontology

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 7168
• Symbol: TPM1
• Description: tropomyosin 1

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
7168	GO:0001725	IDA	located_in	stress fiber	12686598	Component
7168	GO:0005829	IDA	located_in	cytosol		Component
7168	GO:0015629	IDA	located_in	actin cytoskeleton		Component
7168	GO:0032059	IMP	located_in	bleb	12686598	Component
7168	GO:0032587	IDA	located_in	ruffle membrane	12686598	Component

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
7168	GO:0005515	IPI	enables	protein binding	16189514,21516116,25416956,26871637	Function
7168	GO:0008092	IPI	enables	cytoskeletal protein binding	17987659	Function

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
7168	GO:0008360	IMP	involved_in	regulation of cell shape	21817107	Process
7168	GO:0034614	IEP	involved_in	cellular response to reactive oxygen species	12686598	Process
7168	GO:0045214	IMP	involved_in	sarcomere organization	11273725	Process
7168	GO:0055010	IMP	involved_in	ventricular cardiac muscle tissue morphogenesis	11136687	Process
7168	GO:0060048	IMP	involved_in	cardiac muscle contraction	11136687	Process
7168	GO:1904706	IMP	involved_in	negative regulation of vascular associated smooth muscle cell proliferation	21817107	Process
7168	GO:1904753	IMP	involved_in	negative regulation of vascular associated smooth muscle cell migration	21817107	Process