Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 7248
  • Symbol: TSC1
  • Description: TSC complex subunit 1

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
7248 GO:0001952 IMP involved_in regulation of cell-matrix adhesion 10806479 Process
7248 GO:0006407 IMP involved_in rRNA export from nucleus 17308101 Process
7248 GO:0006417 IDA involved_in regulation of translation 17308101 Process
7248 GO:0007160 IMP involved_in cell-matrix adhesion 10806479 Process
7248 GO:0008285 IMP involved_in negative regulation of cell population proliferation 10915759 Process
7248 GO:0017148 IMP involved_in negative regulation of translation 17308101 Process
7248 GO:0032007 IDA involved_in negative regulation of TOR signaling 22795129 Process
7248 GO:0032007 IMP involved_in negative regulation of TOR signaling 17308101,28215400 Process
7248 GO:0032780 IDA involved_in negative regulation of ATP-dependent activity 29127155 Process
7248 GO:0032868 IDA involved_in response to insulin 16996505 Process
7248 GO:0043666 IMP involved_in regulation of phosphoprotein phosphatase activity 17308101 Process
7248 GO:0050821 IDA involved_in protein stabilization 11175345 Process
7248 GO:0050821 IMP involved_in protein stabilization 29127155 Process
7248 GO:0051492 IDA involved_in regulation of stress fiber assembly 10806479 Process
7248 GO:0051894 IDA involved_in positive regulation of focal adhesion assembly 10806479 Process
7248 GO:0090630 IDA involved_in activation of GTPase activity 10806479 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
7248 GO:0005515 IPI enables protein binding 9580671,9809973,10585443,10806479,12226091,17355907,17658474,1..... Function
7248 GO:0030544 IDA enables Hsp70 protein binding 29127155 Function
7248 GO:0042030 IDA enables ATPase inhibitor activity 29127155 Function
7248 GO:0051087 IPI enables protein-folding chaperone binding 10585443 Function
7248 GO:0051879 IPI enables Hsp90 protein binding 29127155 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
7248 GO:0005737 IDA located_in cytoplasm 9580671 Component
7248 GO:0005811 IDA located_in lipid droplet Component
7248 GO:0005829 IDA located_in cytosol 10585443 Component
7248 GO:0005884 IDA colocalizes_with actin filament 10806479 Component
7248 GO:0005938 IDA located_in cell cortex 10806479 Component
7248 GO:0016020 IDA located_in membrane 16636147 Component
7248 GO:0030027 IDA located_in lamellipodium 10806479 Component
7248 GO:0032991 IDA part_of protein-containing complex 10585443 Component
7248 GO:0033596 EXP part_of TSC1-TSC2 complex 26893383 Component
7248 GO:0033596 IDA part_of TSC1-TSC2 complex 9580671 Component
7248 GO:0033596 IPI part_of TSC1-TSC2 complex 22795129 Component
7248 GO:0101031 IDA part_of protein folding chaperone complex 29127155 Component