Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 7249
  • Symbol: TSC2
  • Description: TSC complex subunit 2

Function

Export (tab separated) Export to Excel
GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
7249 GO:0005096 IDA enables GTPase activator activity 9045618 Function
7249 GO:0005515 IPI enables protein binding 9580671,9809973,10585443,12176984,12364343,12582162,15161933,1..... Function
7249 GO:0019902 IDA enables phosphatase binding 19389623 Function
7249 GO:0031267 IPI enables small GTPase binding 25936802 Function
7249 GO:0042803 IPI enables protein homodimerization activity 10585443 Function
7249 GO:0051879 IPI enables Hsp90 protein binding 29127155 Function

Component

Export (tab separated) Export to Excel
GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
7249 GO:0005634 IDA NOT located_in nucleus 16636147 Component
7249 GO:0005634 IDA located_in nucleus 17114346 Component
7249 GO:0005737 IDA colocalizes_with cytoplasm 17114346 Component
7249 GO:0005737 IDA located_in cytoplasm 9580671,16636147 Component
7249 GO:0005764 IDA located_in lysosome 25936802 Component
7249 GO:0005794 IDA NOT located_in Golgi apparatus 10585443 Component
7249 GO:0005794 IDA located_in Golgi apparatus 8806680 Component
7249 GO:0005829 IDA located_in cytosol 10585443 Component
7249 GO:0014069 EXP is_active_in postsynaptic density 27898073 Component
7249 GO:0014069 IDA is_active_in postsynaptic density 27898073 Component
7249 GO:0016020 IDA located_in membrane 16636147 Component
7249 GO:0033596 IDA part_of TSC1-TSC2 complex 9580671 Component
7249 GO:0033596 IPI part_of TSC1-TSC2 complex 22795129 Component
7249 GO:0048471 IDA located_in perinuclear region of cytoplasm 8806680 Component

Process

Export (tab separated) Export to Excel
GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
7249 GO:0016239 IGI involved_in positive regulation of macroautophagy 23778976 Process
7249 GO:0032007 IDA involved_in negative regulation of TOR signaling 22795129 Process
7249 GO:0032007 IGI involved_in negative regulation of TOR signaling 23778976 Process
7249 GO:0043276 IGI involved_in anoikis 23778976 Process