Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 7414
  • Symbol: VCL
  • Description: vinculin

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
7414 GO:0002009 IMP involved_in morphogenesis of an epithelium 20086044 Process
7414 GO:0034333 IMP involved_in adherens junction assembly 20086044 Process
7414 GO:0034394 IMP involved_in protein localization to cell surface 20086044 Process
7414 GO:0043297 IMP involved_in apical junction assembly 9700171 Process
7414 GO:0051893 IMP involved_in regulation of focal adhesion assembly 26923917 Process
7414 GO:0070527 HMP involved_in platelet aggregation 23382103 Process
7414 GO:0090136 IMP involved_in epithelial cell-cell adhesion 20086044 Process
7414 GO:1903140 IDA involved_in regulation of establishment of endothelial barrier 26923917 Process
7414 GO:1904702 IMP involved_in regulation of protein localization to adherens junction 26923917 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
7414 GO:0002162 IPI enables dystroglycan binding 18341635 Function
7414 GO:0003779 IDA NOT enables actin binding 7816144 Function
7414 GO:0003779 IDA enables actin binding 16803572 Function
7414 GO:0005515 IPI enables protein binding 9054445,9885244,10320934,12473693,15070891,15163412,15988023,1..... Function
7414 GO:0031625 IPI enables ubiquitin protein ligase binding 19725078 Function
7414 GO:0045294 IPI enables alpha-catenin binding 9700171 Function
7414 GO:0045296 HDA enables cadherin binding 25468996 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
7414 GO:0005911 IMP located_in cell-cell junction 25753039 Component
7414 GO:0005912 IDA located_in adherens junction 20086044,26923917 Component
7414 GO:0005925 HDA located_in focal adhesion 21423176 Component
7414 GO:0005925 IDA located_in focal adhesion 15070891,20086044,29162887 Component
7414 GO:0005925 IMP located_in focal adhesion 26923917 Component
7414 GO:0032991 IDA part_of protein-containing complex 9700171 Component
7414 GO:0043034 IDA located_in costamere 9415431 Component
7414 GO:0044291 IMP located_in cell-cell contact zone 26923917 Component
7414 GO:0070062 HDA located_in extracellular exosome 19056867,20458337 Component
7414 GO:1903561 HDA located_in extracellular vesicle 24769233 Component