Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 7416
  • Symbol: VDAC1
  • Description: voltage dependent anion channel 1

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
7416 GO:0005515 IPI enables protein binding 9843949,16201016,19130895,21370995,22304920,23055042,25296756,..... Function
7416 GO:0008308 IDA enables voltage-gated monoatomic anion channel activity 8420959 Function
7416 GO:0015485 IDA enables cholesterol binding 31015432 Function
7416 GO:0019901 IPI enables protein kinase binding 21370995 Function
7416 GO:0031210 IDA enables phosphatidylcholine binding 31015432 Function
7416 GO:0042802 IPI enables identical protein binding 18832158 Function
7416 GO:0044325 IPI enables transmembrane transporter binding 25296756 Function
7416 GO:0097001 IDA enables ceramide binding 31015432 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
7416 GO:0005634 HDA located_in nucleus 21630459 Component
7416 GO:0005739 HDA located_in mitochondrion 20833797 Component
7416 GO:0005739 IDA located_in mitochondrion 30188326,31206022 Component
7416 GO:0005741 IDA located_in mitochondrial outer membrane 7539795,17008324,25244949 Component
7416 GO:0005757 IDA part_of mitochondrial permeability transition pore complex 26387735 Component
7416 GO:0005886 IDA located_in plasma membrane 25296756 Component
7416 GO:0016020 IDA located_in membrane 27641616 Component
7416 GO:0031966 IDA located_in mitochondrial membrane 31015432 Component
7416 GO:0042645 IDA located_in mitochondrial nucleoid 18063578 Component
7416 GO:0070062 HDA located_in extracellular exosome 19056867,20458337,23533145 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
7416 GO:0006820 IDA involved_in monoatomic anion transport 8420959 Process
7416 GO:0006915 IDA involved_in apoptotic process 25296756 Process
7416 GO:0030855 IEP involved_in epithelial cell differentiation 21492153 Process
7416 GO:0043066 IMP involved_in negative regulation of apoptotic process 32047033 Process
7416 GO:0110099 IMP involved_in negative regulation of calcium import into the mitochondrion 32047033 Process
7416 GO:1905091 IMP involved_in positive regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization 32047033 Process