Gene Ontology

Gene Info

• Species: Mouse (Mus musculus)
• GeneID: 74769
• Symbol: Pik3cb
• Description: phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
74769	GO:0001935	IMP	acts_upstream_of_or_within	endothelial cell proliferation	25139353	Process
74769	GO:0001952	IMP	acts_upstream_of_or_within	regulation of cell-matrix adhesion	15834429	Process
74769	GO:0002931	IMP	involved_in	response to ischemia	30496354	Process
74769	GO:0003376	IGI	involved_in	sphingosine-1-phosphate receptor signaling pathway	18558630	Process
74769	GO:0006874	IMP	acts_upstream_of_or_within	intracellular calcium ion homeostasis	15834429	Process
74769	GO:0007156	IMP	acts_upstream_of_or_within	homophilic cell adhesion via plasma membrane adhesion molecules	15834429	Process
74769	GO:0010595	IGI	involved_in	positive regulation of endothelial cell migration	18558630	Process
74769	GO:0014065	IGI	involved_in	phosphatidylinositol 3-kinase signaling	18558630	Process
74769	GO:0014065	IMP	involved_in	phosphatidylinositol 3-kinase signaling	30496354	Process
74769	GO:0030168	IMP	acts_upstream_of_or_within	platelet activation	15834429	Process
74769	GO:0035022	IGI	involved_in	positive regulation of Rac protein signal transduction	18558630	Process
74769	GO:0040016	IMP	acts_upstream_of_or_within	embryonic cleavage	11919689	Process
74769	GO:0043407	IMP	involved_in	negative regulation of MAP kinase activity	30496354	Process
74769	GO:0051898	IMP	involved_in	negative regulation of protein kinase B signaling	30496354	Process
74769	GO:0060055	IMP	acts_upstream_of_or_within	angiogenesis involved in wound healing	25139353	Process
74769	GO:1903298	IMP	involved_in	negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway	30496354	Process

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
74769	GO:0005515	IPI	enables	protein binding	15102471,18449193	Function
74769	GO:0016303	IMP	enables	1-phosphatidylinositol-3-kinase activity	15834429,16625210	Function
74769	GO:0043560	IPI	enables	insulin receptor substrate binding	16625210	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
74769	GO:0005634	IDA	located_in	nucleus	30496354	Component