Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 7520
  • Symbol: XRCC5
  • Description: X-ray repair cross complementing 5

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
7520 GO:0000781 HDA located_in chromosome, telomeric region 19135898 Component
7520 GO:0000781 IDA located_in chromosome, telomeric region 10535943 Component
7520 GO:0005634 IDA located_in nucleus 32103174 Component
7520 GO:0005654 IDA located_in nucleoplasm Component
7520 GO:0005730 IDA located_in nucleolus 32103174 Component
7520 GO:0005886 IDA located_in plasma membrane Component
7520 GO:0016020 HDA located_in membrane 19946888 Component
7520 GO:0032040 IDA part_of small-subunit processome 32103174 Component
7520 GO:0032991 IDA part_of protein-containing complex 22504299 Component
7520 GO:0032993 IDA part_of protein-DNA complex 22504299 Component
7520 GO:0043564 IDA part_of Ku70:Ku80 complex 20383123,24095731,26359349 Component
7520 GO:0043564 IPI part_of Ku70:Ku80 complex 11493912 Component
7520 GO:0070418 IPI part_of DNA-dependent protein kinase complex 28840859 Component
7520 GO:0070419 IDA part_of nonhomologous end joining complex 20383123,25941166 Component
7520 GO:0090734 IMP located_in site of DNA damage 27248496 Component
7520 GO:1990904 IDA part_of ribonucleoprotein complex 14704337 Component

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
7520 GO:0000976 IDA enables transcription cis-regulatory region binding 18809223 Function
7520 GO:0003691 IDA contributes_to double-stranded telomeric DNA binding 10409678 Function
7520 GO:0003723 HDA enables RNA binding 22658674,22681889 Function
7520 GO:0003723 IDA enables RNA binding 14704337 Function
7520 GO:0005515 IPI enables protein binding 8621488,10783163,12145306,12377759,14704337,15075319,17159921,..... Function
7520 GO:0008094 IDA enables ATP-dependent activity, acting on DNA 9368068 Function
7520 GO:0016887 IDA enables ATP hydrolysis activity 9368068 Function
7520 GO:0031625 IPI enables ubiquitin protein ligase binding 22266820 Function
7520 GO:0034511 IDA enables U3 snoRNA binding 32103174 Function
7520 GO:0042162 IDA enables telomeric DNA binding 10535943 Function
7520 GO:0044877 IPI enables protein-containing complex binding 12377759 Function
7520 GO:0045027 IDA contributes_to DNA end binding 9368068 Function
7520 GO:0045027 IDA enables DNA end binding 19549901 Function
7520 GO:0051575 IMP contributes_to 5'-deoxyribose-5-phosphate lyase activity 20383123 Function

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
7520 GO:0002218 IDA involved_in activation of innate immune response 28712728 Process
7520 GO:0006302 IMP involved_in double-strand break repair 19581589 Process
7520 GO:0006303 IDA involved_in double-strand break repair via nonhomologous end joining 26359349 Process
7520 GO:0006303 IMP involved_in double-strand break repair via nonhomologous end joining 20383123 Process
7520 GO:0006974 IMP involved_in DNA damage response 27248496 Process
7520 GO:0032212 IMP involved_in positive regulation of telomere maintenance via telomerase 19188702 Process
7520 GO:0034462 IDA involved_in small-subunit processome assembly 32103174 Process
7520 GO:0045860 IDA involved_in positive regulation of protein kinase activity 22504299 Process
7520 GO:0045892 IMP involved_in negative regulation of DNA-templated transcription 8621488 Process
7520 GO:0048660 IMP involved_in regulation of smooth muscle cell proliferation 25852083 Process
7520 GO:0071480 IDA involved_in cellular response to gamma radiation 26359349 Process
7520 GO:1904430 IMP involved_in negative regulation of t-circle formation 19581589 Process