Gene Ontology

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 823
• Symbol: CAPN1
• Description: calpain 1

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
823	GO:0004198	IDA	enables	calcium-dependent cysteine-type endopeptidase activity	2407243,16411745,19617626	Function
823	GO:0005509	IDA	enables	calcium ion binding	9271093	Function
823	GO:0005515	IPI	enables	protein binding	9407132,19712109,21988832,22805611,31324722,32814053.....	Function
823	GO:0008233	IDA	enables	peptidase activity	23707407	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
823	GO:0005829	IDA	located_in	cytosol	8769305,12150984,14559243,21531719	Component
823	GO:0005886	IDA	located_in	plasma membrane	8769305,12150984	Component
823	GO:0005925	HDA	located_in	focal adhesion	21423176	Component
823	GO:0016020	IDA	located_in	membrane	14559243	Component
823	GO:0070062	HDA	located_in	extracellular exosome	19056867,19199708,23533145	Component

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
823	GO:0006508	IDA	involved_in	proteolysis	2400579,2407243,16411745,21531719	Process
823	GO:0050790	IDA	involved_in	regulation of catalytic activity	8954105,9271093	Process
823	GO:0097264	IDA	involved_in	self proteolysis	8769305,8954105	Process