Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 8312
  • Symbol: AXIN1
  • Description: axin 1

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
8312 GO:0001934 IDA involved_in positive regulation of protein phosphorylation 9601641 Process
8312 GO:0032147 IDA involved_in activation of protein kinase activity 9601641 Process
8312 GO:0045732 IDA involved_in positive regulation of protein catabolic process 9601641 Process
8312 GO:0045893 IMP involved_in positive regulation of DNA-templated transcription 16601693 Process
8312 GO:0051443 IMP involved_in positive regulation of ubiquitin-protein transferase activity 16601693 Process
8312 GO:0065003 IDA involved_in protein-containing complex assembly 16601693 Process
8312 GO:0090090 IDA involved_in negative regulation of canonical Wnt signaling pathway 10644691 Process
8312 GO:0090090 IMP involved_in negative regulation of canonical Wnt signaling pathway 22899650 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
8312 GO:0005515 IPI enables protein binding 9601641,10481074,10644691,10811618,11738041,12192039,16169070,..... Function
8312 GO:0008013 IDA enables beta-catenin binding 10644691 Function
8312 GO:0019899 IPI enables enzyme binding 19759537,21383061,21478859 Function
8312 GO:0030159 IMP enables signaling receptor complex adaptor activity 16601693 Function
8312 GO:0031625 IPI enables ubiquitin protein ligase binding 16601693,21478859 Function
8312 GO:0042802 IPI enables identical protein binding 10811618,16169070,21245303 Function
8312 GO:0046332 IPI enables SMAD binding 18593713 Function
8312 GO:0060090 IDA enables molecular adaptor activity 9601641 Function
8312 GO:0060090 IMP enables molecular adaptor activity 16601693 Function
8312 GO:0070411 IPI enables I-SMAD binding 16601693,18593713 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
8312 GO:0005634 IDA located_in nucleus 12072559,21383061 Component
8312 GO:0005737 IDA located_in cytoplasm 12072559,17569865,21383061 Component
8312 GO:0016328 IDA located_in lateral plasma membrane 12072559 Component
8312 GO:0030877 IDA part_of beta-catenin destruction complex 9601641,16188939,19759537 Component
8312 GO:0048471 IDA located_in perinuclear region of cytoplasm 19038973 Component
8312 GO:0071944 IDA located_in cell periphery 19038973 Component