Gene Ontology

Gene Info

• Species: Yeast (Saccharomyces cerevisiae)
• GeneID: 852468
• Symbol: NPL4
• Description: nuclear protein localization protein 4

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
852468	GO:0000837	IDA	part_of	Doa10p ubiquitin ligase complex	16873066	Component
852468	GO:0000839	IDA	part_of	Hrd1p ubiquitin ligase ERAD-L complex	16873065,16873066	Component
852468	GO:0005634	HDA	located_in	nucleus	22842922,26928762	Component
852468	GO:0005737	HDA	located_in	cytoplasm	22842922	Component
852468	GO:0030894	IDA	part_of	replisome	31509741	Component
852468	GO:0034098	IDA	part_of	VCP-NPL4-UFD1 AAA ATPase complex	11598205,11733065	Component
852468	GO:0036266	IDA	part_of	Cdc48p-Npl4p-Vms1p AAA ATPase complex	21070972	Component
852468	GO:0042175	IDA	located_in	nuclear outer membrane-endoplasmic reticulum membrane network	11598205	Component
852468	GO:1990112	IDA	part_of	RQC complex	23178123	Component

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
852468	GO:0006274	IDA	involved_in	DNA replication termination	31509741	Process
852468	GO:0030433	IMP	involved_in	ubiquitin-dependent ERAD pathway	11739805	Process
852468	GO:0030970	IMP	involved_in	retrograde protein transport, ER to cytosol	11740563	Process
852468	GO:0043161	IMP	involved_in	proteasome-mediated ubiquitin-dependent protein catabolic process	20206597	Process
852468	GO:0051228	IMP	involved_in	mitotic spindle disassembly	14636562	Process
852468	GO:0070651	IMP	involved_in	nonfunctional rRNA decay	22505030	Process
852468	GO:0071629	IMP	involved_in	cytoplasm protein quality control by the ubiquitin-proteasome system	18812321	Process
852468	GO:0071712	IMP	involved_in	ER-associated misfolded protein catabolic process	11740563,11813000	Process
852468	GO:0072665	IMP	involved_in	protein localization to vacuole	29444958	Process
852468	GO:0072671	IMP	involved_in	mitochondria-associated ubiquitin-dependent protein catabolic process	21070972,32118579	Process
852468	GO:0099638	IMP	acts_upstream_of_or_within	endosome to plasma membrane protein transport	36125415	Process
852468	GO:1900182	IMP	involved_in	positive regulation of protein localization to nucleus	11598205,11733065	Process
852468	GO:1990116	IMP	involved_in	ribosome-associated ubiquitin-dependent protein catabolic process	23358411	Process

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
852468	GO:0036435	IDA	enables	K48-linked polyubiquitin modification-dependent protein binding	28525741	Function