Gene Ontology

Gene Info

• Species: Yeast (Saccharomyces cerevisiae)
• GeneID: 855264
• Symbol: MRE11
• Description: MRX complex nuclease subunit

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
855264	GO:0000723	IMP	involved_in	telomere maintenance	9501103	Process
855264	GO:0000727	IGI	involved_in	double-strand break repair via break-induced replication	17321803	Process
855264	GO:0000727	IMP	involved_in	double-strand break repair via break-induced replication	17321803	Process
855264	GO:0006281	IMP	involved_in	DNA repair	7789757	Process
855264	GO:0006284	IMP	involved_in	base-excision repair	20040573	Process
855264	GO:0006303	IMP	involved_in	double-strand break repair via nonhomologous end joining	9501103,12399380	Process
855264	GO:0007131	IMP	involved_in	reciprocal meiotic recombination	8417989	Process
855264	GO:0010791	IMP	involved_in	DNA double-strand break processing involved in repair via synthesis-dependent strand annealing	23254329	Process
855264	GO:0030437	IMP	involved_in	ascospore formation	17396017	Process
855264	GO:0035753	IMP	involved_in	maintenance of DNA trinucleotide repeats	27173583	Process
855264	GO:0051037	IMP	involved_in	regulation of transcription involved in meiotic cell cycle	17396017	Process
855264	GO:0097552	IMP	involved_in	mitochondrial double-strand break repair via homologous recombination	22214610	Process

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
855264	GO:0003691	IDA	enables	double-stranded telomeric DNA binding	17698079	Function
855264	GO:0004017	IDA	contributes_to	adenylate kinase activity	17349953	Function
855264	GO:0004519	IDA	enables	endonuclease activity	9858579	Function
855264	GO:0004520	IDA	enables	DNA endonuclease activity	16116037	Function
855264	GO:0008408	IDA	enables	3'-5' exonuclease activity	11454871	Function
855264	GO:0042162	IDA	enables	telomeric DNA binding	15721260,16116037	Function
855264	GO:0043047	IDA	enables	single-stranded telomeric DNA binding	17698079	Function
855264	GO:0051880	IDA	enables	G-quadruplex DNA binding	17698079	Function
855264	GO:0060090	IGI	enables	molecular adaptor activity	9845372	Function
855264	GO:0060090	IMP	enables	molecular adaptor activity	9845372	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
855264	GO:0005634	HDA	located_in	nucleus	22842922	Component
855264	GO:0005634	IDA	located_in	nucleus	9845372,15548595	Component
855264	GO:0005739	HDA	located_in	mitochondrion	14576278,16823961	Component
855264	GO:0030870	IPI	part_of	Mre11 complex	9845372	Component