Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 9113
  • Symbol: LATS1
  • Description: large tumor suppressor kinase 1

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
9113 GO:0000086 IDA involved_in G2/M transition of mitotic cell cycle 15122335 Process
9113 GO:0000819 IDA involved_in sister chromatid segregation 15122335 Process
9113 GO:0006468 IDA involved_in protein phosphorylation 10518011 Process
9113 GO:0030833 IDA involved_in regulation of actin filament polymerization 15220930 Process
9113 GO:0033138 IDA involved_in positive regulation of peptidyl-serine phosphorylation 20412773 Process
9113 GO:0033146 IMP involved_in regulation of intracellular estrogen receptor signaling pathway 28068668 Process
9113 GO:0035329 IDA involved_in hippo signaling 20412773 Process
9113 GO:0043254 IMP involved_in regulation of protein-containing complex assembly 20412773 Process
9113 GO:0045736 IDA involved_in negative regulation of cyclin-dependent protein serine/threonine kinase activity 9988268 Process
9113 GO:0051220 IMP involved_in cytoplasmic sequestering of protein 20412773 Process
9113 GO:0060644 IMP involved_in mammary gland epithelial cell differentiation 28068668 Process
9113 GO:0090090 IMP involved_in negative regulation of canonical Wnt signaling pathway 20412773 Process
9113 GO:2000058 IMP involved_in regulation of ubiquitin-dependent protein catabolic process 28068668 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
9113 GO:0000287 IDA enables magnesium ion binding 10518011 Function
9113 GO:0004674 IDA enables protein serine/threonine kinase activity 10518011,20412773 Function
9113 GO:0005515 IPI enables protein binding 9988268,10831611,15220930,18158288,19739119,19927127,20303269,..... Function
9113 GO:0005524 IDA enables ATP binding 10518011 Function
9113 GO:0019901 IPI enables protein kinase binding 19927127 Function
9113 GO:0030331 IPI enables nuclear estrogen receptor binding 28068668 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
9113 GO:0000922 IDA located_in spindle pole 10518011 Component