| 104318 |
Q9DC28 |
KC1D_MOUSE |
Casein kinase I isoform delta (CKI-delta) (CKId) (EC 2.7.11.1) (Tau-protein kinase CSNK1D) (EC 2.7.11.26) |
DISRUPTION PHENOTYPE |
Lethal. There are fewer embryos than expected at late stages of gestation; they weigh about 30% less than control animals, but appear otherwise normal. Mice die shortly after birth. Tissue-specific disruption increases the half-life of PER2 protein and alters circadian protein expression dynamics. {ECO:0000269|PubMed:19414593, ECO:0000269|PubMed:19948962}. |