Mine Disruption Phenotype

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 110651
  • Symbol: Rps6ka3
  • Description: ribosomal protein S6 kinase polypeptide 3
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Gene ID Entry Entry Name Protein Name Type Information
110651 P18654 KS6A3_MOUSE Ribosomal protein S6 kinase alpha-3 (S6K-alpha-3) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (p90RSK3) (MAP kinase-activated protein kinase 1b) (MAPK-activated protein kinase 1b) (MAPKAP kinase 1b) (MAPKAPK-1b) (Ribosomal S6 kinase 2 DISRUPTION PHENOTYPE Mice were born at expected Mendelian ratio but display decreased bone mass (PubMed:15109498). Embryos and pups show a delay in mineralization of the skull with frontal, parietal, and interparietal bones of reduced size (PubMed:15109498). Mice also display a significant reduction in long bone length at one month of age (PubMed:15109498). {ECO:0000269|PubMed:15109498}.