Mine Disruption Phenotype

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 12861
  • Symbol: Cox6a1
  • Description: cytochrome c oxidase subunit 6A1
Export (tab separated) Export to Excel
Gene ID Entry Entry Name Protein Name Type Information
12861 P43024 CX6A1_MOUSE Cytochrome c oxidase subunit 6A1, mitochondrial (Cytochrome c oxidase polypeptide VIa-liver) DISRUPTION PHENOTYPE Mice have walking difficulties. Histologic examination shows thinned sciatic nerves and neurogenic muscular changes, including small angular fibers and small group atrophy. Electrophysiologic studies show delayed motor nerve conduction velocities compared to controls. COX activity and ATP contents in liver cells are decreased. {ECO:0000269|PubMed:25152455}.