Mine Disruption Phenotype

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 12988
  • Symbol: Csk
  • Description: c-src tyrosine kinase
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Gene ID Entry Entry Name Protein Name Type Information
12988 P41241 CSK_MOUSE Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-Src kinase) (Protein-tyrosine kinase MPK-2) (p50CSK) DISRUPTION PHENOTYPE Mice die between day 9 and day 10 of gestation with several defects including a non-functional neural tube. SRC and FYN kinases show increased activity when CSK is missing. {ECO:0000269|PubMed:7685657}.