Mine Disruption Phenotype

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 13478
  • Symbol: Dpagt1
  • Description: dolichyl-phosphate N-acetylglucosaminephosphotransferase 1
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Gene ID Entry Entry Name Protein Name Type Information
13478 P42867 GPT_MOUSE UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase (EC 2.7.8.15) (GlcNAc-1-P transferase) (G1PT) (GPT) (N-acetylglucosamine-1-phosphate transferase) DISRUPTION PHENOTYPE Mice die 4 to 5 days post-fertilization, just after implantation, suggesting that protein function and N-glycosylation are essential in early embryogenesis. {ECO:0000269|PubMed:10536042}.