| 13508 |
Q9ERC8 |
DSCAM_MOUSE |
Cell adhesion molecule DSCAM (Down syndrome cell adhesion molecule homolog) |
DISRUPTION PHENOTYPE |
The ganglion cell layer and developing inner plexiform layer in the retina are disorganised at postnatal day 4 (P4). This desorganisation persisted into adulthood in amacrine and ganglions cells. Amacrine and ganglion cell populations show fasciculated dendrites that self-crossed and their cell bodies are randomly distributed or pulled into clumps. {ECO:0000269|PubMed:18216855, ECO:0000269|PubMed:19945391}. |