| 13649 |
Q01279 |
EGFR_MOUSE |
Epidermal growth factor receptor (EC 2.7.10.1) |
DISRUPTION PHENOTYPE |
Mice are growth retarded and die at different stages of development depending on their genetic background. Embryonic death is due to placental defects. Mice surviving until birth or later display brain, bone, heart and various epithelial development defects in several organs, including skin, lung and gastrointestinal tract. {ECO:0000269|PubMed:7618084, ECO:0000269|PubMed:7618085, ECO:0000269|PubMed:7630400}. |