| Gene ID | Entry | Entry Name | Protein Name | Type | Information | 13860 | Q08509 | EPS8_MOUSE | Epidermal growth factor receptor kinase substrate 8 | DISRUPTION PHENOTYPE | No visible phenotype. Defects in PDGF-induced membrane ruffling due to defects in Ras to Rac signals. Dendritic cells are impaired in directional and chemotactic migration and are delayed in reaching the draining lymph node in vivo after inflammatory challenge. Mice show short stereocilia. {ECO:0000269|PubMed:10499589, ECO:0000269|PubMed:21236676, ECO:0000269|PubMed:21835647}. |
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