| Gene ID | Entry | Entry Name | Protein Name | Type | Information | 16846 | P41160 | LEP_MOUSE | Leptin (Obesity factor) | DISRUPTION PHENOTYPE | Mutants are severely obese and sterile (PubMed:8589726). Animals have an increased bone formation leading to high bone mass (PubMed:10660043). Have impaired T-cell immunity, Th2 responses are favoured in mutants (PubMed:9732873). CD4(+)CD25(-) T-cells of mutant mice show high levels of autophagy (PubMed:25060689). {ECO:0000269|PubMed:10660043, ECO:0000269|PubMed:25060689, ECO:0000269|PubMed:8589726, ECO:0000269|PubMed:9732873}. |
|---|