| 17906 |
P51667 |
MLRV_MOUSE |
Myosin regulatory light chain 2, ventricular/cardiac muscle isoform (MLC-2) (MLC-2v) (Myosin light chain 2, slow skeletal/ventricular muscle isoform) (MLC-2s/v) |
DISRUPTION PHENOTYPE |
Myl2 homozygous die at 12.5 dpc, which is associated with ultrastructural defects in ventricular sarcomere assembly, that included disruptions and disorganization of the normal parallel alignment of the thick and thin filaments, narrower fiber widths and larger distances between Z disks and misalignment of Z-band between sarcomeres. {ECO:0000269|PubMed:9422794}. |