| 17926 |
O70624 |
MYOC_MOUSE |
Myocilin (Trabecular meshwork-induced glucocorticoid response protein) [Cleaved into: Myocilin, N-terminal fragment (Myocilin 20 kDa N-terminal fragment); Myocilin, C-terminal fragment (Myocilin 35 kDa N-terminal fragment)] |
DISRUPTION PHENOTYPE |
Mice lacking Myoc are viable, fertile and show no significant differences in intraocular pressure or clinical signs of glaucoma. They also show a reduction in cortical bone thickness as well as trabecular volume. {ECO:0000269|PubMed:23629661}. |