| 18632 |
Q9Z210 |
PX11B_MOUSE |
Peroxisomal membrane protein 11B (Peroxin-11B) (Peroxisomal biogenesis factor 11B) (Protein PEX11 homolog beta) (PEX11-beta) |
DISRUPTION PHENOTYPE |
Mice have a marked decrease in peroxisome abundance. They share several phenotypes with Zellweger syndrome mouse models, including neuronal migration defects, hypotonia, a developmental delay, and neonatal lethality but no detectable defect in peroxisomal protein import and only mild defects in peroxisomal metabolic function. {ECO:0000269|PubMed:12024045}. |