Mine Disruption Phenotype

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 18663
  • Symbol: Pgk2
  • Description: phosphoglycerate kinase 2
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Gene ID Entry Entry Name Protein Name Type Information
18663 P09041 PGK2_MOUSE Phosphoglycerate kinase 2 (EC 2.7.2.3) (Phosphoglycerate kinase, testis specific) DISRUPTION PHENOTYPE Mice display greatly reduced ATP levels in sperm, severely impaired sperm motility and are infertile. No alteration in testis histology, sperm counts, or sperm ultrastructure seen. {ECO:0000269|PubMed:19759366}.