Mine Disruption Phenotype

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 19056
  • Symbol: Ppp3cb
  • Description: protein phosphatase 3, catalytic subunit, beta isoform
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Gene ID Entry Entry Name Protein Name Type Information
19056 P48453 PP2BB_MOUSE Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform (EC 3.1.3.16) (CAM-PRP catalytic subunit) (Calmodulin-dependent calcineurin A subunit beta isoform) (CNA beta) DISRUPTION PHENOTYPE Knockout mice show reduced body weight, independent of changes in muscle weight (PubMed:12773574). Reduced slow and intermediate program type muscle fibers in the biceps, triceps and soleus (PubMed:12773574). Increased expression of fast program type muscle fibers in the soleus muscle (PubMed:12773574). {ECO:0000269|PubMed:12773574}.