Mine Disruption Phenotype

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 19353
  • Symbol: Rac1
  • Description: Rac family small GTPase 1
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Gene ID Entry Entry Name Protein Name Type Information
19353 P63001 RAC1_MOUSE Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (p21-Rac1) DISRUPTION PHENOTYPE Conditional knockout of Rac1 in the telencephalic ventricular zone of embryos leads to primary microcephaly. Self-renewal, survival, and differentiation of telencephalic neural progenitor cells is affected. {ECO:0000269|PubMed:19007770}.