Mine Disruption Phenotype

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 20603
  • Symbol: Sms
  • Description: spermine synthase
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Gene ID Entry Entry Name Protein Name Type Information
20603 P97355 SPSY_MOUSE Spermine synthase (SPMSY) (EC 2.5.1.22) (Spermidine aminopropyltransferase) DISRUPTION PHENOTYPE Mouse ES cells lacking Sms display normal growth rates but are sensitive to antiproliferative and DNA damage-inducing drugs. {ECO:0000269|PubMed:15459188, ECO:0000269|PubMed:9467015}.