| 217480 |
Q6NS52 |
DGKB_MOUSE |
Diacylglycerol kinase beta (DAG kinase beta) (EC 2.7.1.107) (Diglyceride kinase beta) (DGK-beta) |
DISRUPTION PHENOTYPE |
Homozygous knockout mice are viable and fertile with no significant difference in weight (PubMed:20657643). However, long-term potentiation (LTP) and cognitive functions including spatial and long-term memory are affected in these mice (PubMed:20657643). A decrease in the total length of neurites and branches together with a reduced number of neurite spines are observed (PubMed:20657643). {ECO:0000269|PubMed:20657643}. |