Mine Disruption Phenotype

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 23821
  • Symbol: Bace1
  • Description: beta-site APP cleaving enzyme 1
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Gene ID Entry Entry Name Protein Name Type Information
23821 P56818 BACE1_MOUSE Beta-secretase 1 (EC 3.4.23.46) (Aspartyl protease 2) (ASP2) (Asp 2) (Beta-site amyloid precursor protein cleaving enzyme 1) (Beta-site APP cleaving enzyme 1) (Memapsin-2) (Membrane-associated aspartic protease 2) DISRUPTION PHENOTYPE Mice show a higher mortality rate early in life. {ECO:0000269|PubMed:15987683, ECO:0000269|PubMed:25592972}.