Mine Disruption Phenotype

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 238384
  • Symbol: Slc24a4
  • Description: solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
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Gene ID Entry Entry Name Protein Name Type Information
238384 Q8CGQ8 NCKX4_MOUSE Sodium/potassium/calcium exchanger 4 (Na(+)/K(+)/Ca(2+)-exchange protein 4) (Solute carrier family 24 member 4) DISRUPTION PHENOTYPE Mice have a reduced ability to locate an odorous source and lower body weights. The olfactory sensory neurons display defects in response termination and adaptation but have unchanged sensitivity (PubMed:22057188). Mice show severe enamel defects (PubMed:23375655). {ECO:0000269|PubMed:22057188, ECO:0000269|PubMed:23375655}.