Mine Disruption Phenotype

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 26900
  • Symbol: Ddx3y
  • Description: DEAD box helicase 3, Y-linked
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Gene ID Entry Entry Name Protein Name Type Information
26900 Q62095 DDX3Y_MOUSE ATP-dependent RNA helicase DDX3Y (EC 3.6.4.13) (D1Pas1-related sequence 1) (DEAD box protein 3, Y-chromosomal) (DEAD-box RNA helicase DEAD2) (mDEAD2) DISRUPTION PHENOTYPE Knockout males show normal spermatogenesis, produce morphologically normal spermatozoa and sire healthy offspring (PubMed:30613052). DDX3X and DDX3Y double knockout is embryonic lethal (PubMed:30613052). DDX3X and DDX3Y double knockout germ cells can differentiate into spermatozoa (PubMed:30613052). {ECO:0000269|PubMed:30613052}.