Mine Disruption Phenotype

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 271564
  • Symbol: Vps13a
  • Description: vacuolar protein sorting 13A
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Gene ID Entry Entry Name Protein Name Type Information
271564 Q5H8C4 VP13A_MOUSE Intermembrane lipid transfer protein VPS13A (Chorea-acanthocytosis protein homolog) (Chorein) (Vacuolar protein sorting-associated protein 13A) DISRUPTION PHENOTYPE Mice show defects in motor coordination, social investigation, erythrocyte morphology as well as size and morphology of the striatum. Provides a mouse model for chorea-acanthocytosis (CHAC) with a mild phenotype and late adult onset. {ECO:0000269|PubMed:15686477}.