Mine Disruption Phenotype

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 382018
  • Symbol: Unc13a
  • Description: unc-13 homolog A
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Gene ID Entry Entry Name Protein Name Type Information
382018 Q4KUS2 UN13A_MOUSE Protein unc-13 homolog A (Munc13-1) DISRUPTION PHENOTYPE Mice display normal synapse formation but abnormal synaptic vesicle maturation and die shortly after birth. Heterozygotes exhibit impaired insulin secretion and abnormal glucose tolerance. {ECO:0000269|PubMed:10440375}.