Mine Disruption Phenotype

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 52014
  • Symbol: Nus1
  • Description: NUS1 dehydrodolichyl diphosphate synthase subunit
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Gene ID Entry Entry Name Protein Name Type Information
52014 Q99LJ8 NGBR_MOUSE Dehydrodolichyl diphosphate synthase complex subunit Nus1 (EC 2.5.1.87) (Nogo-B receptor) (NgBR) (Nuclear undecaprenyl pyrophosphate synthase 1 homolog) DISRUPTION PHENOTYPE Leads to early embryonic lethality in vivo and defective cis-prenyltransferase activity and cholesterol levels in isolated fibroblasts. {ECO:0000269|PubMed:25066056}.