Mine Disruption Phenotype

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 54137
  • Symbol: Acrbp
  • Description: proacrosin binding protein
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Gene ID Entry Entry Name Protein Name Type Information
54137 Q3V140 ACRBP_MOUSE Acrosin-binding protein (Acrosin-binding protein, 60 kDa form) (Proacrosin-binding protein sp32) [Cleaved into: Acrosin-binding protein, mature form (ACRPB-C) (Acrosin-binding protein, 32 kDa form, mature form) (Sp32)] DISRUPTION PHENOTYPE Deficient male and female are normal in behavior, body size, and health condition. Females exhibit normal fertility. However, males exhibit a severely reduced fertility. The acrosomal structure of spermatids is severely deformed at the later steps of spermiogenesis. {ECO:0000269|PubMed:27303034}.